Hepeviridae Study Group

The Hepevirdae study group intends to post genome alignments of genera and species within the family in the near future.

The Table below gives a summary of the current taxonomic structure of the Hepeviridaeas as proposed in: Smith, D. B., Simmonds, P., Jameel, S., Emerson, S. U., Harrison, T. J., Meng, X.-J., Okamoto, H., Van der Poel, W. H. M. & Purdy, M. A. (2014). Consensus proposals for classification of the family Hepeviridae. J Gen Virol 95, 2223–32 and ratified by the ICTV.

Genus	Species	Genotype	Prototype / Reference strain	Predominant host species	GenBank accession
Genus	Species	Genotype	Prototype / Reference strain	Predominant host species	GenBank accession
Orthohepevirus			Burma	Human	M73218
	Orthohepevirus A	HEV-1	Burma	Human	M73218
		HEV-2	Mexico	Human	M74506
		HEV-3	Meng	Human, pig, rabbit, deer, mongoose	AF082843
		HEV-4	T1	Human, pig	AJ272108
		HEV-5	JBOAR135-Shiz09	Wild boar	AB573435
		HEV-6	wbJOY_06	Wild boar	AB602441
		HEV-7	DcHEV-178C	Camel	KJ496143
	Orthohepevirus B		F93-5077	Chicken	AY535004
	Orthohepevirus C	HEV-C1	R63	Rat	GU345042
	Orthohepevirus C	HEV-C2	FRHEV4	Ferret	JN998606
	Orthohepevirus D		BatHEV/BS7/GE/2009	Bat	JQ001749
Piscihepevirus			Heenan Lake	Trout	HQ731075
	Piscihepevirus A		Heenan Lake	Trout	HQ731075

Reference sequences for subtypes of Orthohepvirus A have been proposed in: Smith, D. B., Simmonds, P., Izopet, J., Oliveira-Filho, E. F., Ulrich, R. G., Johne, R., Koenig, M., Jameel, S., Harrison, T. J., Meng X-J., Okamoto H., van der Poel W.H.M. and Purdy M.A. (2016). Proposed reference sequences for Hepatitis E virus subtypes. J Gen Virol. (in press, doi: 10.1099/jgv.0.000393). A Table summarising these reference sequences is available here.