Genus: Copiparvovirus


Genus: Copiparvovirus

Distinguishing features

Viruses in genus Copiparvovirus share a major branch in the phylogenetic tree of subfamily Parvovirinae with the homotelomeric viruses in genera Dependoparvovirus, Erythroparvovirus and Tetraparvovirus (Figure 6B.Parvoviridae). Copiparvoviruses are distinguished by being monophyletic and by sequence identity criteria. However, because implemented alignment methods have changed since these identity guidelines were first adopted, less than 30% apparent identity in the NS1 amino acid sequence is now accepted to accommodate the founder porcine parvovirus 4 (PPV4) and bovine parvovirus 2 (BPV2) genomes. Most known viruses were identified in domestic cows or pigs using virus discovery approaches, and are relatively common, but it is not clear whether they are associated with disease. To date no viruses from this genus have been isolated and their molecular biology remains to be explored.

Virion 

See discussion under family description.

Genome organization and replication

The genome structures and genetic organization of these viruses appear similar but detailed protein expression profiles have yet to be determined. 

Antigenicity 

See discussion under family description.

Biology

See discussion under family description.

Species demarcation criteria 

Viruses within a species are monophyletic and encode replication initiator proteins (called NS1 or Rep1, 68, or 78) that show >85% amino acid sequence identity.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Ungulate copiparvovirus 1bovine parvovirus 2AF406966NC_006259Complete coding genomeBPV2
Ungulate copiparvovirus 2porcine parvovirus 417GQ387499NC_014665Complete coding genomePPV4

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Related, unclassified viruses 

Virus name

Accession number

Virus abbreviation

porcine parvovirus 6

KX384823

PPV6

bosavirus

KY019139

BosaV

equine parvovirus-hepatitis

MG136722

EqPV-H

Virus names and virus abbreviations are not official ICTV designations.