Distinguishing features
Fabaviruses have bipartite genomes encapsidated by two capsid proteins (CP) and are transmitted by aphids.
Virion
See discussion under family description.
Genome organisation and replication
The genomic organization of fabaviruses is similar to that of comoviruses. Similar to comoviruses, RNA-2 encodes two overlapping polyproteins with the N-terminal protein playing a role in the replication of RNA-2 and the overlapping movement protein being synthesized through initiation at the second AUG codon (Lin et al., 2014). The movement protein was also confirmed to be a structural component of the tubular structures that traverse the cell wall (Liu et al., 2011) (Figure 3.Secoviridae). The cleavage of polyproteins is presumed to be similar to that of comoviruses but this has not been investigated in detail.
Biology
Fabaviruses have wide host ranges among dicotyledonous plants and some families of monocotyledonous plants. Symptoms are ringspots, mottling, mosaic, distortion, wilting and apical necrosis. In nature, fabaviruses are transmitted by aphids in a non-persistent manner.
Species demarcation criteria
See discussion under family description.
Member species
| Species | Virus name | Isolate | Accession number | RefSeq number | Available sequence | Virus Abbrev. | |
|---|---|---|---|---|---|---|---|
| Broad bean wilt virus 1 | broad bean wilt virus 1 | ATCC PV132 | RNA-1: AB084450; RNA-2: AB084451 All | RNA-1: NC_005289; RNA-2: NC_005290 All | Complete genome | BBWV1 | |
| Broad bean wilt virus 2 | broad bean wilt virus 2 | ME | RNA-1: AF225953; RNA-2: AF225954 All | RNA-1: NC_003003; RNA-2: NC_003004 All | Complete genome | BBWV2 | |
| Cucurbit mild mosaic virus | cucurbit mild mosaic virus | Beijing | RNA-1: EU881936; RNA-2: EU881937 All | RNA-1: NC_038760; RNA-2: NC_038759 All | Complete genome | CuMMV | |
| Fabavirus PLPaV | peach leaf pitting-associated virus A | KY867750; KY867751 All | Complete genome | PLPaV | |||
| Gentian mosaic virus | gentian mosaic virus | N-1 | RNA-1: AB084452; RNA-2: AB084453 All | Complete genome | GeMV | ||
| Grapevine fabavirus | Grapevine fabavirus | NP | RNA-1: KX241482; RNA-2: KX241485 All | RNA-1: NC_039073; RNA-2: NC_039072 All | Complete coding genome | GFabV | |
| Lamium mild mosaic virus | Lamium mild mosaic virus | DSMZ PV-0454 | RNA-1: KC595304; RNA-2: KC595305 All | RNA-1: NC_023016; RNA-2: NC_023017 All | Complete genome | LMMV | |
| Prunus virus F | Prunus virus F | 8816-v1 | RNA-1: KX269865; RNA-2: KX269871 All | RNA-1: NC_039077; RNA-2: NC_039078 All | Complete genome | PrVF |