The genus is distinguished on the basis of genetic characters.
No details are available on the morphology of virions.
Genome (Wu et al., 2012, Kemenesi et al., 2015): c. 8,457 nt (5′-UTR: up to 1,407 nt; ORF: 6750–6,846 nt; 3′-UTR: up to 220 nt). The 5′-UTR is exceptionally long. The location of the cre has not been identified.
Genome organization and replication
VPg+5′-UTRIRES-II- [L-1AB-1C-1D-2Anpgp/2B-2C/3A-3B-3C-3D] -3′-UTR-poly(A)
The deduced polyprotein is of 2,282 aa. There is likely an L protein of unknown function. 2A is a short polypeptide with an NPG↓P motif.
The natural host is likely the common bent-wing bat (Miniopterus schreibersii) and the groundleaf giant bat (Hipposideros gigas). No virus has been isolated. Viral RNA was detected in pharyngeal and anal swabs of apparently healthy bats.
Derivation of names
Mischivirus: from the host species Miniopterus schreibersii (common bent-wing bat)
Species demarcation criteria
Members of a species of the genus Mischivirus:
- are less than 30% divergent in polyprotein aa sequence
- are less than 30% divergent in P1 aa sequence
- are less than 25% divergent in 2C + 3CD aa sequence
- share a common genome organization
|Species||Virus name||Isolate||Accession number||RefSeq number||Available sequence||Virus Abbrev.|
|Mischivirus A||mischivirus A1; Minopterus schreibersii picornavirus||bat/China/2010||JQ814851||NC_034381||Complete genome||MiV-A1|
|Mischivirus B||mischivirus B1; bat picornavirus||batPV/V1/13/Hun||KP054273||NC_043072||Complete genome||MiV-B1|
|Mischivirus C||mischivirus C1; African bat icavirus||TNo13||KP100644||NC_026470||Complete genome||MiV-C1|
|Mischivirus D||mischivirus D1; canine picornavirus||A128thr||KY512802||Complete genome||MiV-D1|
|Mischivirus E||mischivirus E1; Suncus murinus mischivirus||Wencheng-Sm294||MF352410||Complete genome||MiV-E1|