The genus is distinguished on the basis of genetic characters.
No details are available on the morphology of virions.
Genome (S. Yang, Y. Wang, and W. Zhang, unpublished): c. 7,104–7,917 nt (5′-UTR: up to 675 nt; ORF: 6,534–7,137 nt; 3′-UTR: 33–105 nt). The location of the cre has not been identified.
Genome organization and replication
grusopivirus A1, A2: VPg+5′-UTRIRES-[1AB-1C-1D-2A1npgp/2A2npgp/2A3npgp/2A4H-box/NC-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)
grusopivirus B1: VPg+5′-UTRIRES-[1AB-1C-1D/2A-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)
The deduced polyprotein is of 2,178–2,379 amino acids. There is no L protein. The 1AB protein remains uncleaved. The 1C/1D processing site is unclear. Two variant 2A gene regions distinguish the members of Grusopivirus A and Grusopivirus B. Grusopivirus A1 and -A2 have three copies of 2A with NPG↓P motif plus a 2A with H-box/NC motif whereas the 2A protein of grusopivirus 2A has an unknown function.
No virus has been isolated. Viral RNA was detected in faecal samples of red-crowned cranes (Grus japonensis). Three genetic types are distinguished by means of phylogenetic analysis (Grusopivirus A: 2 types, Grusopivirus B: 1 type).
Derivation of names
Grusopivirus: derived from Grus japonensis (host) and picornavirus
Species demarcation criteria
Members of a species of the genus Grusopivirus:
- are less than 30% divergent in polyprotein aa sequence
- are less than 30% divergent in P1 aa sequence
- are less than 20% divergent in 2C+3CD aa sequence
|Species||Virus name||Isolate||Accession number||RefSeq number||Available sequence||Virus Abbrev.|
|Grusopivirus A||grusopivirus A1; crane picornavirus 5||yc-5||KY312544||Complete genome||GruhV-A1|
|Grusopivirus B||grusopivirus B1; crane picornavirus 6||yc-6||KY312545||Complete genome||GruhV-B1|
|Grusopivirus C||grusopivirus C1; lorikeet picornavirus||LoPV-1||MK443503||Complete genome||GruV-C1|
Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Related, unclassified viruses
crane picornavirus 4 [yc-4]