Picornaviridae

Genus: Avisivirus


Genus: Avisivirus

Virion

Morphology

Unknown

Physicochemical and physical properties

Unknown

Nucleic acid

Length of genome (Lau et al., 2014): c. 7,530 nt (5'-UTR: 548; ORF: 6,498-6,720; 3'-UTR: 264 nt). 5' UTR contains a type II IRES. The location of the cre has not been identified.

Genome organization and replication

Genome layout: 

VPg+5'UTRIRES-II[1AB-1C-1D-(2A1npgp)/2A2npgp/2A3NTPase-2A4H-box/NC-2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of 2,165-2,239 amino acids. There is no L protein. The 1AB protein remains uncleaved. Avisiviruses have three to four 2A proteins, i.e. one or two short FMDV-like (2A1 and 2A2) with NPG¯P motif, 2A3 with P-loop NTPase sequence motifs and 2A4 with H-box/NC motif.

Biology

Viral RNA was detected in faeces of turkeys (Meleagris gallopavo) and chickens (Gallus gallus domesticus) with gastrointestinal disease. 

Species demarcation criteria

Members of a species of the genus Avisivirus share a common genome organization.

The divergence (number of differences per site between sequences) of known Avisivirus species ranges from 0.53-0.59 for P1 and 0.46-0.49 for 3CD. Four types have been classified by means of phylogenetic clustering (AsV-A1, AsV-B1, AsV-C1, -C2).

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)
Avisivirus Aavisivirus AKC614703Complete genomeAsV-A
Avisivirus Bavisivirus B; chicken picornavirus 2KF979333NC_024766Complete genomeASV-B
Avisivirus Cavisivirus C; chicken picornavirus 3KF979334NC_024767Complete genomeAsV-C

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Avisi: from Avihepato sister-clade

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  • When: Aug 1, 2017 2:06 PM
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  • When: Sep 1, 2017 1:34 PM
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