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The genus is distinguished on the basis of genetic characters.
No details are available on the morphology of the virions.
Genome (Lau et al., 2014): c. 7,530 nt (5′-UTR: 548; ORF: 6,498–6,720; 3′-UTR: 264 nt). 5′-UTR contains a type II IRES. The location of the cre has not been identified.
The deduced polyprotein is of 2,165–2,239 amino acids. There is no L protein. The 1AB protein remains uncleaved. Avisiviruses have three to four 2A proteins, i.e. one or two short foot-and-mouth disease virus-like (2A1 and 2A2) with NPG¯P motif, 2A3 with AIG1-type guanine nucleotide-binding domain (GxxGxGKS NTP-binding motif) and 2A4 with H-box/NC motif.
Viral RNA was detected in faeces of turkeys (Meleagris gallopavo) and chickens (Gallus gallus domesticus) with gastrointestinal disease.
Avisi-: from Avihepato sister-clade
Members of a species of the genus Avisivirus share a common genome organization.
The divergence (number of differences per site between sequences) between members of different Avisivirus species ranges from 0.53–0.59 for P1 and 0.46–0.49 for 3CD. Four types have been classified by means of phylogenetic clustering (AsV-A1, AsV-B1, AsV-C1, -C2).
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