Genus: Salivirus


Genus: Salivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No details are available on the morphology of the virions.

Nucleic acid

Genome (Li et al., 2009, Greninger et al., 2009, Holtz et al., 2009): 7,982–8,021 nt (5′-UTR: 709–763 nt; ORF: 7,110–7,125 nt; 3′-UTR: 148 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5′-UTRIRES-V-[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)

The deduced polyprotein is of 2,374 amino acids. There is a L protein with unknown function. 1AB remains uncleaved. 2A protein has no H-box/NC sequence motif. 

Antigenicity

See discussion under family description.

Biology

Viral RNA was detected in faeces of humans with gastroenteritis and non-polio acute flaccid paralysis and of chimpanzees. 

Species demarcation criteria

There is only a single species in the genus, Salivirus A, which includes two genetic types (Yu et al., 2015, Aldabbagh et al., 2015, Ng et al., 2012).

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Salivirus Asalivirus A1hu/NG-J1/Nigeria/2007GQ179640NC_012957Complete genomeSaV-A1
Salivirus Asalivirus A2hu/FHB/China/2011KM023140SaV-A2

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Sali-: from stool aichi-like 

These viruses have also been named klassevirus for kobu-like viruses associated with stool and sewage (Greninger et al., 2009).