Picornaviridae

Genus: Rosavirus


Genus: Rosavirus

Virion 

Nucleic acid

Length of genome (Du et al., 2016, Phan et al., 2011, Lim et al., 2014): c. 8,931 nt (5'-UTR: up to 828 nt; ORF: 7,413 nt; 3' UTR: up to 795 nt). 5'-UTR harbours a type II IRES. 3'-UTR is the longest of picornaviruses. The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5'UTRIRES-II[1AB-1C-1D-2Anpgp/2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of 2,468 aa. 1AB remains uncleaved. 2A is an aphthovirus-like polypeptide with NPG¯P motif.

Biology

Viral RNA was detected in faecal samples of human and rodents [canyon mouse (Peromyscus crinitus), rat (Rattus norvegicus)].

Species demarcation criteria

The single species Rosavirus A includes two genetic types.

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)
Rosavirus Arosavirus A1JF973686Coding complete genomeRoV-A1

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Rosa: from rodent stool-associated

Related, Unclassified Viruses

Further related genome sequences have been identified in rats (Rattus norvegicus, R. andamanensis, R. rattus, R. losea, Niviventer fulvescens and N. coxingi) which probably belong to two new rosavirus species.

Virus name

Accession number

Virus abbreviation

Rosavirus B1

[rat/RNCW0602091R/HKN/2009]

KX783423

RoV-B1

Rosavirus C1

[rat/RATLC11A/HKN/2009]

KX783425

RoV-C1

Rosavirus C2

[rat/RASK8F/HKN/2008]

KX783424

RoV-C2

Rosavirus C2

 [rodent/RL/PicoV/FJ2015]

KX156156

RoV-C2

Rosavirus C3

[rat/NCGX12IN/CHA/2010]

KX783432

RoV-C3

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.
  • Created by
  • When: Aug 1, 2017 2:06 PM
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  • When: Sep 21, 2017 2:37 AM
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