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Length of genome (Du et al., 2016, Phan et al., 2011, Lim et al., 2014): c. 8,931 nt (5'-UTR: up to 828 nt; ORF: 7,413 nt; 3' UTR: up to 795 nt). 5'-UTR harbours a type II IRES. 3'-UTR is the longest of picornaviruses. The location of the cre has not been identified.
The deduced polyprotein has a length of 2,468 aa. 1AB remains uncleaved. 2A is an aphthovirus-like polypeptide with NPG¯P motif.
Viral RNA was detected in faecal samples of human and rodents [canyon mouse (Peromyscus crinitus), rat (Rattus norvegicus)].
The single species Rosavirus A includes two genetic types.
Rosa: from rodent stool-associated
Further related genome sequences have been identified in rats (Rattus norvegicus, R. andamanensis, R. rattus, R. losea, Niviventer fulvescens and N. coxingi) which probably belong to two new rosavirus species.
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