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The genus is distinguished on the basis of genetic characters.
No details are available on the morphology of the virions.
Genome (Du et al., 2016, Phan et al., 2011, Lim et al., 2014, Lau et al., 2016): c. 8,931 nt (5′-UTR: 504-721 nt; ORF: 7,410-7,449 nt; 3′-UTR: 712-946 nt). 5′-UTR harbours a type II IRES. 3′-UTR is the longest of picornaviruses. The location of the cre has not been identified.
Genome layout:
VPg+5′-UTRIRES-II-[1A-1B-1C-1D-2AH-box/NC/2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)
The deduced polyprotein is of 2,468-2,491 aa. 2A has a H-box/NC motif.
See discussion under family description.
Viral RNA was detected in faecal samples of humans and rodents [canyon mouse (Peromyscus crinitus), brown rat (Rattus norvegicus), black rat (R. rattus), Sikkim rat (R. andamanensis), chestnut white-bellied rat (Niviventer fulvescens)]. Available sequence data suggest 8 types.
Members of a species of genus Rosavirus:
Rosavirus A and Rosavirus B both include two genetic types, while Rosavirus C includes four genetic types.
Rosa-: from rodent stool-associated