Genus: Rabovirus


Genus: Rabovirus

Virion

Morphology

Virus has not yet been isolated.

Nucleic acid

Length of genome (Ng et al., 2015): 7,834 nt (5'-UTR: 751 nt; ORF: 7,005 nt; 3'-UTR: 78 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5'UTRIRES-II[L/1A-1B-1C-1D/2Apro-2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of 2,335 amino acids. The L protein has unknown function. The 2A protein has been proposed to be chymotrypsin-like protease. 

Antigenicity

See discussion under family description.

Biology

Viral RNA was detected in faeces of Norway rats (Rattus norvegicus) in USA and Germany.

Species demarcation criteria

Divergence of P1 sequences suggest the single species Rabovirus A may include two types.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Rabovirus Arabovirus ABerlin/Jan2011/0572KP233897NC_026314Partial genomeRaBoV-A

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Rabo: from rat-borne