Genus: Pasivirus


Genus: Pasivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No details are available on the morphology of the virions.

Nucleic acid

Genome (Sauvage et al., 2012, Boros et al., 2015a, Yu et al., 2013): c. 6,938 nt (5′-UTR: c. 420 nt; ORF: c. 6,402 nt; 3′-UTR: 136 nt). The location of the cre has not been identified. 

Genome organization and replication

Genome layout:

VPg+5′-UTRIRES-IV-[1AB-1C-1D-2A1npgp/-2A2-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)

The deduced polyprotein is of c. 2,133 aa. There is no L protein. 1AB protein remains uncleaved. The aphthovirus-like 2A1 protein has a NPG¯P sequence motif; the function of 2A2 is unknown. 3Dpol of all known pasiviruses has the motif ASG rather than PSG. 

Antigenicity

See discussion under family description.

Biology

The natural host is likely the domestic pig (Sus scrofa). Viral RNA has been detected in faeces of pigs.

Species demarcation criteria

There is only a single species in the genus.

 Four types have been classified by means of phylogenetic clustering.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Pasivirus Apasivirus A1; swine pasivirusswine/France/2011JQ316470NC_018226Complete genomePaV-A1
Pasivirus Apasivirus A2PVL-CHN (pig/China/2010)JX491648PaV-A2
Pasivirus Apasivirus A3swine/Zsana1/2013/HUN (pig/Hungary/2013)KM259923PaV-A3

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Pasi-: from parecho sister-clade