Genus: Pasivirus


Genus: Pasivirus

Virion

Nucleic acid

Length of genome (Sauvage et al., 2012, Boros et al., 2015, Yu et al., 2013): c. 6,938 nt (5'-UTR: c. 420 nt; ORF: c. 6,402 nt; 3' UTR: 136 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5'UTRIRES-IV[1AB-1C-1D-2A1npgp/-2A2-2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of c. 2,133 aa. There is no L protein. 1AB protein remains uncleaved. The aphthovirus-like 2A1 protein has a NPG¯P sequence motif; the function of 2A2 is unknown. 3Dpol has a deviant ASG motif.

Biology

The natural host is likely the domestic pig (Sus scrofa). Viral RNA has been detected in faeces of pigs.

Species demarcation criteria

Members of a species of the genus Pasivirus:

  • share greater than 70% aa identity in P1,
  • share greater than 80% aa identity in 2C + 3CD,
  • share a common genome organization.

The divergence (number of differences per site between sequences) of known Pasivirus species ranges from 0.66-0.67 for P1 and 0.63-0.64 for 3CD. 

Three types have been classified by means of phylogenetic clustering.

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Pasivirus Apasivirus A; swine pasivirusswine/France/2011JQ316470NC_018226Complete genomePaV-A

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Pasi: from parecho sister-clade