Genus: Mosavirus

Genus: Mosavirus


Nucleic acid

Length of genome (Phan et al., 2011, Reuter et al., 2014): c. 8,385 nt (5'-UTR: >646 nt; ORF: 7,653 nt; 3' UTR: 86 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:


The deduced polyprotein has a length of 2,551 aa. There is a L protein which may be a protease. 2A is an aphthovirus-like polypeptide with NPG¯P motif. The genome is predicted to encode a second 3B (VPg) protein. The 3Cpro has a deviant GxCGx10-15AxH motif.


Viral RNA was detected in faeces of the canyon mouse (Peromyscus crinitus) and the European roller (Coriacas garrulus). Phylogenetically these viruses fall into two distinct types.

Species demarcation criteria

Members of a species of the genus Mosavirus:

  • share greater than 65% aa identity in P1,
  • share greater than 80% aa identity in 2C + 3CD,
  • share a common genome organization.

The divergence (number of differences per site between sequences) of known Mosavirus species ranges from 0.6-0.61 for P1 and 0.58-0.6 for 3CD.

Two genetic types have been classified by means of phylogenetic clustering.

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)
Mosavirus Amosavirus A1JF973687Complete genomeMoV-A

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Mosa: from mouse stool-associated

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  • When: Aug 1, 2017 2:06 PM
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