Genus: Mosavirus


Genus: Mosavirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No details are available on the morphology of the virions. 

Nucleic acid

Genome (Phan et al., 2011, Reuter et al., 2014): c. 8,385 nt (5′-UTR: >646 nt; ORF: 7,653 nt; 3′-UTR: 86 nt). The location of the cre has not been identified. 

Genome organization and replication

Genome layout

VPg+5′-UTRIRES-II-[L/1A-1B-1C-1D-2Anpgp/2B-2C/3A-3B1-3B2-3C-3D]-3′-UTR-poly(A)

The deduced polyprotein is of 2,551 aa. There is a L protein which may be a protease. 2A is an aphthovirus-like polypeptide with NPG↓P motif. The genome is predicted to encode a second 3B (VPg) protein. The 3Cpro has a deviant GxCGx10-15AxH motif. 

Antigenicity

See discussion under family description.

Biology

Viral RNA was detected in faeces of the canyon mouse (Peromyscus crinitus) and the European roller (Coriacas garrulus).

Species demarcation criteria

There is only a single species in the genus.

Two genetic types have been classified by means of phylogenetic clustering.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Mosavirus Amosavirus A1mouse/M-7/USA/2010JF973687NC_038318Complete genomeMoV-A1
Mosavirus Amosavirus A2SZAL6-MoV/2011/HUNKF958461MoV-A2

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Mosa-: from mouse stool-associated

Related, unclassified viruses 

Virus name

Accession number

Virus abbreviation

marmot mosavirus [TH8/China/2013]

KY855435

 

Virus names and virus abbreviations are not official ICTV designations.

Phylogenetic analysis indicates that this virus may be a member of a novel Mosavirus species.