Genus: Mischivirus

Virion

Nucleic acid

Length of genome (Wu et al., 2012, Kemenesi et al., 2015): c. 8,457 nt (5'-UTR: 1,407 nt; ORF: 6,846 nt; 3'-UTR: 204 nt). 5' UTR is exceptionally long. The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5'UTR^IRES-II[L/1AB-1C-1D-2A^npgp/2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of 2,282 aa. There is likely a L protein. 2A is a short FMDV-like polypeptide with NPG¯P motif.

Biology

The natural host is likely the common bent-wing bat (Miniopterus schreibersii) and the groundleaf giant bat (Hipposideros gigas). Viral RNA was detected in pharyngeal and anal swabs of apparently healthy bats. 

Species demarcation criteria

Members of a species of the genus Mischivirus share a common genome organization.

The divergence (number of differences per site between sequences) of known Mischivirus species ranges from 0.27-0.57 for P1 and 0.2-0.45 for 3CD.

Member Species

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Mischi: Miniopterus schreibersii (common bent-wing bat)

Related, Unclassified Viruses