Picornaviridae

Genus: Limnipivirus


Genus: Limnipivirus

Virion

Morphology

No surface morphology of the icosahedral capsid is visible by EM.

Nucleic acid

Length of genome (Lange et al., 2014, Barbknecht et al., 2014, Phelps et al., 2014): c. 7700-8050 nt (5'-UTR: >501-712 nt; ORF: 6810-7011 nt; 3'-UTR: 312-363 nt). 5' UTR contains a type IV IRES. The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5'UTRIRES-IV[1AB-1C-1D-2A1npgp/2A2npgp/-2B-2C/3A-3B-3C-3D]3'UTR-poly(A)

The deduced polyprotein has a length of 2,337 aa. There is no L protein. 1AB remains uncleaved and has a N-terminal myristoylation signal. There are two aphthovirus-like 2A proteins with NPG↓P motif.

Biology

Limnipiviruses infect freshwater fish. The virus can be grown in various fish cell lines. Experimental infection of bluegills with bluegill picornavirus induces morbidity (inflammation and redness at the base of fins, exophthalmia, abdomen distension, internal hemorrhaging and ascites) and mortality.

Species demarcation criteria

Members of a species of the genus Limnipivirus share a common genome organization.

The divergence (number of differences per site between sequences) of known Limnipivirus species ranges from 0.3-0.43 for P1 and 0.49-0.57 for 3CD. 

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)
Limnipivirus Abluegill picornavirusJX134222NC_018506Complete genomeBGPV
Limnipivirus Bcarp picornavirus KF306267NC_023162Complete genomeCPV
Limnipivirus Cfathead minnow picornavirusKF183915Complete genomeFHMPV

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.
Download GenBank/EMBL query for sequences listed in the table here.

Derivation of names

Limnipi: from Greek limne, 'lake', and pi from picornavirus.

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  • When: Aug 1, 2017 2:06 PM
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  • When: Aug 30, 2017 11:46 PM
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