Genus: Hunnivirus


Genus: Hunnivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No surface morphology is visible on the 28 nm particles by EM.

Nucleic acid

Genome (Reuter et al., 2012, Firth et al., 2014, Du et al., 2016): 7,496–7,588 nt (5′-UTR: 715–732 nt; ORF: 6,729–6,819 nt; 3′-UTR: 114–119 nt). The 5′-UTR contains a type II IRES. The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5′-UTRIRES-II-[L-1A-1B-1C-1D-2Anpgp/2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)

The deduced polyprotein is of 2,243–2,273 aa. There is an L protein with unknown function. 2A is a short polypeptide with an NPG↓P motif.

Biology

Viral RNA was detected in the faeces of cattle, sheep and rats. One virus (HuV-A3), from sheep, has been isolated in lamb kidney cell cultures in which it caused a CPE. Nine genetic types are distinguished by means of phylogenetic analysis. 

Derivation of names

Hunnivirus: from Hungary and Northern Ireland

Species demarcation criteria

There is only a single species in the genus.

Member species

Exemplar isolate of the species
SpeciesVirus nameIsolateAccession numberRefSeq numberAvailable sequenceVirus Abbrev.
Hunnivirus Ahunnivirus A1; bovine hungaroviruscattle/HUN/2008JQ941880NC_018668Complete genomeHuV-A1
Hunnivirus Ahunnivirus A2; ovine hungarovirus 1sheep/HUN/2009HM153767Complete genomeHuV-A2
Hunnivirus Ahunnivirus A4; Norway rat hunnivirusrat/Rn/PicoV/SX2015-2KX156157Complete genomeHuV-A4
Hunnivirus Ahunnivirus A583GR-70-RAT048/Vietnam/2012KT944199Partial genomeHuV-A5
Hunnivirus Ahunnivirus A6rodent/Rn/PicoV/SX2015-2KX156157Complete genomeHuV-A6
Hunnivirus Ahunnivirus A705VZ-75-RAT099KT944214Complete genomeHuV-A7
Hunnivirus Ahunnivirus A883GR-70-RAT106KT944212Complete genomeHuV-A8
Hunnivirus Ahunnivirus A9RtRrs-PicoV/YN2014KY432925Complete genomeHuV-A9

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.