Genus: Hunnivirus

Genus: Hunnivirus



No surface morphology is visible on the 28 nm particles by EM.

Nucleic acid

Length of genome (Reuter et al., 2012, Firth et al., 2014, Du et al., 2016): 7,496-7,588 nt (5'-UTR: 715-732 nt; ORF: 7,425 nt; 3'-UTR: 114-119 nt). 5' UTR contains a type II IRES. The location of the cre has not been identified.

Genome organization and replication

Genome layout:


The deduced polyprotein has a length of 2,474 aa. There is a L protein with unknown function. 2A is a short FMDV type A-like polypeptide with NPG¯P motif.


See discussion under family description.


Viral RNA was detected in the faeces of cattle, sheep and rats. One virus (HuV-A3), from sheep, has been isolated in lamb kidney cell cultures in which it caused a CPE.

Species demarcation criteria

Members of a species of the genus Hunnivirus share a common genome organization.

The divergence (number of differences per site between sequences) of known Hunnivirus species ranges from 0.54-0.58 for P1 and 0.49-0.5 for 3CD. There are three genetic types, one found in cattle, two in sheep. Phylogenetic analyses suggest that hunniviruses from rats form a second species containing three genetic types.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Hunnivirus Ahunnivirus A1; bovine hungaroviruscattle/HUN/2008JQ941880NC_018668Complete genomeHuV-A1

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Hunni: from Hungary and Northern Ireland

Related, unclassified viruses 

Virus name

Accession number

Virus abbreviation

Hunnivirus 05VZ-75-RAT099



Hunnivirus 83GR-70-RAT106



Hunnivirus 83GR-70-RAT051



Virus names and virus abbreviations are not official ICTV designations.