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The genus is distinguished on the basis of genetic characters.
No surface morphology is visible on the 28 nm particles by EM.
Genome (Reuter et al., 2012, Firth et al., 2014, Du et al., 2016): 7,496–7,588 nt (5′-UTR: 715–732 nt; ORF: 6,729–6,819 nt; 3′-UTR: 114–119 nt). The 5′-UTR contains a type II IRES. The location of the cre has not been identified.
The deduced polyprotein is of 2,243–2,273 aa. There is an L protein with unknown function. 2A is a short polypeptide with an NPG↓P motif.
Viral RNA was detected in the faeces of cattle, sheep and rats. One virus (HuV-A3), from sheep, has been isolated in lamb kidney cell cultures in which it caused a CPE. Nine genetic types are distinguished by means of phylogenetic analysis.
Hunnivirus: from Hungary and Northern Ireland
There is only a single species in the genus.
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