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No surface morphology is visible on the 28 nm particles by EM.
Length of genome (Reuter et al., 2012, Firth et al., 2014, Du et al., 2016): 7,496-7,588 nt (5'-UTR: 715-732 nt; ORF: 7,425 nt; 3'-UTR: 114-119 nt). 5' UTR contains a type II IRES. The location of the cre has not been identified.
The deduced polyprotein has a length of 2,474 aa. There is a L protein with unknown function. 2A is a short FMDV type A-like polypeptide with NPG¯P motif.
See discussion under family description.
Viral RNA was detected in the faeces of cattle, sheep and rats. One virus (HuV-A3), from sheep, has been isolated in lamb kidney cell cultures in which it caused a CPE.
Members of a species of the genus Hunnivirus share a common genome organization.
The divergence (number of differences per site between sequences) of known Hunnivirus species ranges from 0.54-0.58 for P1 and 0.49-0.5 for 3CD. There are three genetic types, one found in cattle, two in sheep. Phylogenetic analyses suggest that hunniviruses from rats form a second species containing three genetic types.
Hunni: from Hungary and Northern Ireland
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