Genus: Malagasivirus

Genus: Malagasivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.



No details are available on the morphology of the virions.

Nucleic acid

Genome (Lim et al., 2015): 7,571-7,593 nt (5′–UTR: 818-869 nt; ORF: 6,618-6,702 nt; 3′–UTR: 116-157 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:


The deduced polyprotein ranges from 2,206 to 2,234 aa. 2A is a short foot-and-mouth disease virus-like polypeptide with NPG↓P motif.


Lesavirus 1 (Malagasivirus A) was detected in faecal specimens of ring-tailed lemurs (Lemur catta), whereas lesavirus 2 (Malagasivirus B) was prevalent in faeces of black-and-white ruffed lemurs. 

Derivation of names

Malagasi refers to the Madagascan (Malagasy) origin of the two lemur species

Species demarcation criteria

Members of a species of genus Malagasivirus:

  • share a common genome organization,
  • are less than 30% divergent in the polyprotein aa sequence,
  • are less than 30% divergent in the P1 aa sequence,
  • are less than 30% divergent in the 2C + 3CD aa sequence. 

Member species

Exemplar isolate of the species
SpeciesVirus nameIsolateAccession numberRefSeq numberAvailable sequenceVirus Abbrev.
Malagasivirus Amalagasivirus A1; lesavirus 1Mis101308/2012KM396707NC_026313Complete genomeMalV-A1
Malagasivirus Bmalagasivirus B1; lesavirus 2Nai108015/2012KM396708NC_026316Complete genomeMalV-B1

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.