Genus: Malagasivirus


Genus: Malagasivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No details are available on the morphology of the virions.

Nucleic acid

Genome (Lim et al., 2015): 7,571-7,593 nt (5′–UTR: 818-869 nt; ORF: 6,618-6,702 nt; 3′–UTR: 116-157 nt). The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5′-UTR-[L-1A-1B-1C-1D-2Anpgp/2B-2C/3A-3B-3C-3D]-3′-UTR

The deduced polyprotein ranges from 2,206 to 2,234 aa. 2A is a short foot-and-mouth disease virus-like polypeptide with NPG↓P motif.

Antigenicity

See discussion under family description.

Biology

Lesavirus 1 (Malagasivirus A) was detected in faecal specimens of ring-tailed lemurs (Lemur catta), whereas lesavirus 2 (Malagasivirus B) was prevalent in faeces of black-and-white ruffed lemurs. 

Species demarcation criteria

Members of a species of genus Malagasivirus:

  • share a common genome organization,
  • are less than 30% divergent in the polyprotein aa sequence,
  • are less than 30% divergent in the P1 aa sequence,
  • are less than 30% divergent in the 2C + 3CD aa sequence. 

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Malagasivirus Amalagasivirus A1; lesavirus 1Mis101308/2012KM396707NC_026313Complete genomeMalV-A1
Malagasivirus Bmalagasivirus B1; lesavirus 2Nai108015/2012KM396708NC_026316Complete genomeMalV-B1

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Malagasi refers to the Madagascan (Malagasy) origin of the two lemur species