Genus: Crohivirus


Genus: Crohivirus

Distinguishing features

The genus is distinguished on the basis of genetic characters.

Virion

Morphology

No details are available on the morphology of the virions. 

Nucleic acid

Genome: 7,085–7,321 nt (5′-UTR: c. 517 nt; ORF: 6,510–6,519 nt; 3′-UTR: >58–294 nt) (Sasaki et al., 2015, Yinda et al., 2017). The location of the cre has not been identified.

Genome organization and replication

Genome layout:

VPg+5′-UTRIRES-[1AB-1C-1D-2A1npgp/2A2H-box/NC-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)

The deduced polyprotein is c. 2,170 amino acids. There is no L protein. The 1AB protein remains uncleaved.

Antigenicity

See discussion under family description.

Biology

Viral RNA was detected in faeces and intestinal contents, respectively, of wild shrews in Zambia and fruit bats (Eidolon helvum) in Cameroon. 

Species demarcation criteria

Members of a species of the genus Crohivirus:

  • share a common genome organization,
  • are less than 55% divergent in polyprotein aa sequence,
  • are less than 60% divergent in P1 aa sequence,
  • are less than 50% divergent in 2C + 3CD aa sequence

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Crohivirus Ashrew crohivirusshrew/ZAM/ZM54/2012AB937989NC_025474Complete coding genomeSCrV
Crohivirus Bbat crohivirusbat/CAM/CroV-P25/2013KX644937NC_033819Complete coding genomeBCrV

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.

Derivation of names

Crohi-: from Crocidura hirta (the lesser red musk shrew from which the first strain was isolated)