Shangavirus RNA has been found in a mixed-insect pool from China containing both chrysopids (green lacewings) and moth flies (Psychoda alternata) (Li et al., 2015). There currently is no cultured shangavirus isolate.
The shangavirus genome consists of three segments of negative-sense RNA (Li et al., 2015). Analysis of the terminal sequences has yet to be completed.
In silico analysis of shangavirus putative ORF sequences suggests shangaviruses encode a protein with RNA-directed RNA polymerase and endonuclease functions (L), the glycoproteins Gn and Gc, the non-structural protein NSm, and the nucleoprotein N, but not the non-structural protein NSs (Table 2.Peribunyaviridae; Figure 1.Shangavirus) (Li et al., 2015).
There are 1 and 9 N-glycosylation sites on Gn and Gc, respectively (Li et al., 2015).
Genome organization and replication
The shangavirus genome is similar to the genomes of all peribunyaviruses. The S, M, and L segments putatively encode N, Gn and Gc, and L proteins, respectively (Li et al., 2015).
Figure 1.Shangavirus. Shangavirus coding strategy. vcRNAs are depicted in 3'→5' direction and mRNAs are depicted in a 5'→3' direction. The mRNAs depict ORFs that encode the N, nucleocapsid protein; Gn and Gc, external glycoproteins; L, large protein, as well as the non-structural protein NSm.
The shangavirus mode of replication is unknown.
Unknown, but suggested to be an insect-specific virus.
Derivation of names
Shangavirus from Shuāngào insect virus 1
Species demarcation criteria
The genus currently includes only a single species.
|Species||Virus name||Isolate||Accession number||RefSeq number||Available sequence||Virus Abbrev.|
|Insect shangavirus||Shuāngào insect virus 1||QSA02||L: KM817679; M: KM817714; S: KM817739||L: NC_031221; M: NC_031222; S: NC_031223||Complete coding genome||SgIV-1|