Genus: Betapolyomavirus


Genus: Betapolyomavirus

Distinguishing features

The best-studied human polyomaviruses, BK polyomavirus (BKPyV) and JC polyomavirus (JCPyV) belong to this genus and are associated with nephropathy and progressive multifocal leukoencephalopathy, respectively.

Virion

See discussion under family description.

Genome organization and replication

See discussion under family description.

Antigenicity

See discussion under family description.

Biology

See discussion under family description.

Species demarcation criteria

  1. Sufficient information on the natural host
  2. Observed genetic distance from a member of the most closely related species is >15% nucleotide difference for the LTAg coding sequence
  3. When two polyomaviruses exhibit <15% observed genetic distance (as defined above), biological properties may be of additional critical importance (e.g. host specificity, disease association, tissue tropism, etc.)

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)Isolate Abbreviation
Acerodon celebensis polyomavirus 2bat polyomavirus 6aBatPyV6aAB972941NC_026762Complete genomeBatPyV6a
Artibeus planirostris polyomavirus 1bat polyomavirus 2cBatPyV2cJQ958887Complete genomeBatPyV2c
Cebus albifrons polyomavirus 1Cebus albifrons polyomavirus 12141JX159988NC_019854Complete genomeCalbPyV1
Cercopithecus erythrotis polyomavirus 1Cercopithecus erythrotis polyomavirus 14077JX159985NC_025892Complete genomeCeryPyV1
Chlorocebus pygerythrus polyomavirus 2vervet monkey polyomavirus 2VMK96AB767299NC_025896Complete genomeVmPyV2
Desmodus rotundus polyomavirus 1bat polyomavirus 2aAT7JQ958892NC_028122Complete genomeBatPyV2a
Dobsonia moluccensis polyomavirus 2bat polyomavirus 6bBatPyV6bAB972947NC_026770Complete genomeBatPyV6b
Dobsonia moluccensis polyomavirus 3bat polyomavirus 6cBatPyV6cAB972946NC_026769Complete genomeBatPyV6c
Equus caballus polyomavirus 1equine polyomavirus CU03JQ412134NC_017982Complete genomeEPyV
Human polyomavirus 1BK polyomavirusDunlopV01108NC_001538Complete genomeBK virus; BKV; BKPyV
Human polyomavirus 2JC polyomavirusMad1J02226NC_001699Complete genomeJC virus; JCV; JCPyV
Human polyomavirus 3KI polyomavirusStockholm 60EF127906NC_009238Complete genomeKIPyV
Human polyomavirus 4WU polyomavirusB0EF444549NC_009539Complete genomeWU virus; WUPyV
Leptonychotes weddellii polyomavirus 1Weddell seal polyomavirus 17461KX533457NC_032120Complete genomeWsPyV
Loxodonta africana polyomavirus 1African elephant polyomavirus 1DK/1/2011KF147833NC_022519Complete genomeAelPyV1
Macaca mulatta polyomavirus 1simian virus 40776J02400NC_001669Complete genomeSV40
Mastomys natalensis polyomavirus 1Mastomys polyomavirusNR55AB588640NC_025895Complete genomeMasPyV
Meles meles polyomavirus 1Meles meles polyomavirus 1FrenchKP644238NC_026473Complete genomeMmelPyV1
Microtus arvalis polyomavirus 1Microtus arvalis polyomavirus 1KR612373NC_028119Complete genomeCVPyV
Miniopterus africanus polyomavirus 1Miniopterus polyomavirusKY369JX520661NC_020069Complete genomeMiniopterusPyV
Mus musculus polyomavirus 2mouse pneumotropic virus6018KT987216Complete genomeMPtV
Myodes glareolus polyomavirus 1Myodes glareolus polyomavirus 1KR612368NC_028117Complete genomeBVPyV
Myotis lucifugus polyomavirus 1Myotis polyomavirusVM2008_14FJ188392NC_011310Complete genomeMyPyV
Pan troglodytes polyomavirus 8Pan troglodytes verus polyomavirus 8Ch-ReginaKT884050NC_028635Complete genomePtrovPyV8
Papio cynocephalus polyomavirus 2yellow baboon polyomavirus 2BS94/BK94AB767295Complete genomeYbPyV2
Pteronotus davyi polyomavirus 1Pteronotus polyomavirusGTM203JX520662NC_020070Complete genomePteronotusPyV
Pteronotus parnellii polyomavirus 1bat polyomavirus 2bR226JQ958891NC_028121Complete genomeBatPyV2b
Rattus norvegicus polyomavirus 2rat polyomavirus 2 PITT4KX574453Complete genomeRatPyV2
Saimiri boliviensis polyomavirus 1squirrel monkey polyomavirusSqui0106AM748741NC_009951Complete genomeSquiPyV
Saimiri sciureus polyomavirus 1Saimiri sciureus polyomavirus 12033JX159989Complete genomeSsciPyV1
Vicugna pacos polyomavirus 1alpaca polyomavirus UCD1KU879245NC_034251Complete genomeAlPyV
Zalophus californianus polyomavirus 1California sea lion polyomavirus 1CSL6994GQ331138NC_013796Complete genomeSLPyV

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.