Genus: Alphapolyomavirus


Genus: Alphapolyomavirus

Distinguishing features

Members infect humans and other mammals. Merkel cell polyomavirus (MCPyV) and raccoon polyomavirus RacPyV) are so far the only members known to cause cancer in their natural host.

Virion

See discussion under family description.

Genome organization and replication

See discussion under family description.

Antigenicity

See discussion under family description.

Biology

See discussion under family description.

Species demarcation criteria

  1. Sufficient information on the natural host
  2. Observed genetic distance from a member of the most closely related species is >15% nucleotide difference for the LTAg coding sequence
  3. When two polyomaviruses exhibit <15% observed genetic distance (as defined above), biological properties may be of additional critical importance (e.g. host specificity, disease association, tissue tropism, etc.)

Member Species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus Abbreviation(s)Isolate Abbreviation
Acerodon celebensis polyomavirus 1bat polyomavirus 5b22AB972940Complete genomeBatPyV5b-2
Artibeus planirostris polyomavirus 2bat polyomavirus 3a-A1055A1055JQ958886Complete genomeBatPyV3a-A1055
Artibeus planirostris polyomavirus 3bat polyomavirus 4aA504JQ958890Complete genomeBatPyV4a
Ateles paniscus polyomavirus 1Ateles paniscus polyomavirus 11960JX159987NC_019853Complete genomeApanPyV1
Cardioderma cor polyomavirus 1Cardioderma polyomavirusKY336JX520659NC_020067Complete genomeCardiodermaPyV
Carollia perspicillata polyomavirus 1bat polyomavirus 4bC1109JQ958889NC_028120Complete genomeBatPyV4b
Chlorocebus pygerythrus polyomavirus 1vervet monkey polyomavirus 1VMS96AB767298NC_019844Complete genomeVmPyV1
Chlorocebus pygerythrus polyomavirus 3vervet monkey polyomavirus 3VMS95/97AB767297NC_025898Complete genomeVmPyV3
Dobsonia moluccensis polyomavirus 1bat polyomavirus 5aBatPyV5aAB972945NC_026768Complete genomeBatPyV5a
Eidolon helvum polyomavirus 1Eidolon polyomavirus 1KY270JX520660NC_020068Complete genomeEidolonPyV
Gorilla gorilla polyomavirus 1Gorilla gorilla gorilla polyomavirus 15766HQ385752NC_025380Complete genomeGgorgPyV1
Human polyomavirus 12human polyomavirus 121403JX308829NC_020890Complete genomeHPyV12
Human polyomavirus 13New Jersey polyomavirus2013KF954417NC_024118Complete genomeNJPyV
Human polyomavirus 5Merkel cell polyomavirusR17bHM011556NC_010277Complete genomeMCPyV
Human polyomavirus 8Trichodysplasia spinulosa-associated polyomavirusSkinGU989205NC_014361Complete genomeTSPyV
Human polyomavirus 9human polyomavirus 92540HQ696595NC_015150Complete genomeHPyV9
Macaca fascicularis polyomavirus 1Macaca fascicularis polyomavirus 12085JX159986NC_019851Complete genomeMfasPyV1
Mesocricetus auratus polyomavirus 1hamster polyomavirusBuchJX036360NC_001663Complete genomeHaPyV
Molossus molossus polyomavirus 1bat polyomavirus 3bB1130JQ958893NC_028123Complete genomeBatPyV3b
Mus musculus polyomavirus 1mouse polyomavirusBGAF442959NC_001515Complete genomeMPyV
Otomops martiensseni polyomavirus 1Otomops polyomavirus 1KY157JX520664NC_020071Complete genomeOtomopsPyV1
Otomops martiensseni polyomavirus 2Otomops polyomavirus 2KY156JX520658NC_020066Complete genomeOtomopsPyV2
Pan troglodytes polyomavirus 1chimpanzee polyomavirusBobFR692334NC_014743Complete genomeChPyV
Pan troglodytes polyomavirus 2Pan troglodytes verus polyomavirus 1a6444HQ385746NC_025368Complete genomePtrovPyV1a
Pan troglodytes polyomavirus 3Pan troglodytes verus polyomavirus 2a6512HQ385748NC_025370Complete genomePtrovPyV2a
Pan troglodytes polyomavirus 4Pan troglodytes verus polyomavirus 33161JX159980NC_019855Complete genomePtrovPyV3
Pan troglodytes polyomavirus 5Pan troglodytes verus polyomavirus 43147JX159981NC_019856Complete genomePtrovPyV4
Pan troglodytes polyomavirus 6Pan troglodytes verus polyomavirus 55743JX159982NC_019857Complete genomePtrovPyV5
Pan troglodytes polyomavirus 7Pan troglodytes schweinfurthii polyomavirus 26350JX159983NC_019858Complete genomePtrosPyV2
Papio cynocephalus polyomavirus 1yellow baboon polyomavirus 1 BS20AB767294NC_025894Complete genomeYbPyV1
Piliocolobus badius polyomavirus 1Piliocolobus badius polyomavirus 2 5947KX509984Complete genomePbadPyV2
Piliocolobus rufomitratus polyomavirus 1Piliocolobus rufomitratus polyomavirus 14601JX159984NC_019850Complete genomePrufPyV1
Pongo abelii polyomavirus 1Sumatran orang-utan polyomavirusSum/PiFN356901NC_028127Complete genomeOraPyV-Sum
Pongo pygmaeus polyomavirus 1Bornean orang-utan polyomavirusBoFN356900NC_013439Complete genomeOraPyV-Bor
Procyon lotor polyomavirus 1raccoon polyomavirusR45JQ178241NC_023845Complete genomeRacPyV
Pteropus vampyrus polyomavirus 1bat polyomavirus 5b11AB972944NC_026767Complete genomeBatPyV5b-1
Rattus norvegicus polyomavirus 1Rattus norvegicus polyomavirus 13690KR075943NC_027531Complete genomeRnorPyV1
Sturnira lilium polyomavirus 1bat polyomavirus 3a-B0454B0454JQ958888Complete genomeBatPyV3a-B0454

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.