Genus: Upsilonpapillomavirus


Genus: Upsilonpapillomavirus

Distinguishing features

Members of this genus are associated with genital lesions in cetaceans. There is evidence for (intra-genus) recombination. Members of this genus lack an E7 ORF.

Virion

See discussion under family description

Genome organization and replication

See discussion under family description.

Antigenicity

See discussion under family description.

Biology

See discussion under family description.

Species demarcation criteria

Putative novel papillomavirus genome with complete genome sequence data available and that is <70% related to papillomaviruses within the genus (Figure 1.Upsilonpapillomavirus).

Figure 1.Upsilonpapillomavirus. Phylogenetic tree of members of the genus Upsilonpapillomavirus. The E1, E2, L2, and L1 nucleotide sequences of 343 papillomavirus isolates including representatives of all species and genera within the Papillomaviridae family were aligned as amino acid sequences using MUSCLE v7.221 (Edgar 2004). JModeltest2 (Darriba et al., 2012) was used to determine the optimal model of evolution (GTR + I + G) for the concatenated nucleotide sequences. Maximum likelihood (ML) trees were constructed using RAxML MPI v8.2.9 (Stamatakis 2006) implementing the GTR substitution model. ML bootstrap analysis used the autoMRE-based stopping criterion in RAxML. Following tree construction (tree available in the Resources section of the Papillomaviridae Report), the subtree corresponding to the genus Upsilonpapillomavirus was isolated. Tips are labelled with virus names and accession numbers; nodes are labelled with bootstrap support values.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Upsilonpapillomavirus 1Tursiops truncatus papillomavirus 1EU240894NC_011109Complete genomeTtPV1
Upsilonpapillomavirus 1Tursiops truncatus papillomavirus 3EU240895TtPV3
Upsilonpapillomavirus 1Delphinus delphis papillomavirus 1GU117620DdPV1
Upsilonpapillomavirus 1Tursiops truncatus papillomavirus 4Tt08-09-4JN709469TtPV4
Upsilonpapillomavirus 1Tursiops truncatus papillomavirus 7Tt09-43JN709472TtPV7
Upsilonpapillomavirus 2Tursiops truncatus papillomavirus 2AY956402NC_008184Complete genomeTtPV2
Upsilonpapillomavirus 3Phocoena phocoena papillomavirus 2GU117622NC_018075Complete genomePphPV2

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.