Genus: Deltapapillomavirus


Genus: Deltapapillomavirus

Distinguishing features

These viruses are associated with fibropapillomas in their respective ungulate hosts. Trans-species transmission occurs, where it induces non-productive sarcoids. The E5 protein, located in the region between the early and late genes, has transforming properties.

Virion

See discussion under family description

Genome organization and replication

See discussion under family description.

Antigenicity

See discussion under family description.

Biology

See discussion under family description.

Species demarcation criteria

Putative novel papillomavirus genome with complete genome sequence data available and that is <70% related to papillomaviruses within the genus (Figure 1.Deltapapillomavirus).

Figure 1.Deltapapillomavirus. Phylogenetic tree of members of the genus Deltapapillomavirus. The E1, E2, L2, and L1 nucleotide sequences of 343 papillomavirus isolates including representatives of all species and genera within the Papillomaviridae family were aligned as amino acid sequences using MUSCLE v7.221 (Edgar 2004). JModeltest2 (Darriba et al., 2012) was used to determine the optimal model of evolution (GTR + I + G) for the concatenated nucleotide sequences. Maximum likelihood (ML) trees were constructed using RAxML MPI v8.2.9 (Stamatakis 2006) implementing the GTR substitution model. ML bootstrap analysis used the autoMRE-based stopping criterion in RAxML. Following tree construction (tree available in the Resources section of the Papillomaviridae Report), the subtree corresponding to the genus Deltapapillomavirus was isolated. Tips are labelled with virus names and accession numbers; nodes are labelled with bootstrap support values.

Member species

SpeciesVirus name(s)Exemplar isolateExemplar accession numberExemplar RefSeq numberAvailable sequenceOther isolatesOther isolate accession numbersVirus abbreviationIsolate abbreviation
Deltapapillomavirus 1Alces alces papillomavirus 1M15953NC_001524Complete genomeAaPV1
Deltapapillomavirus 1Rangifer tarandus papillomavirus 1AF443292RtPV1
Deltapapillomavirus 2Odocoileus virginianus papillomavirus 1M11910NC_001523Complete genomeOvPV1
Deltapapillomavirus 3Ovis aries papillomavirus 1U83594NC_001789Complete genomeOaPV1
Deltapapillomavirus 3Ovis aries papillomavirus 2U83595OaPV2
Deltapapillomavirus 4Bos taurus papillomavirus 1X02346NC_001522Complete genomeBPV1
Deltapapillomavirus 4Bos taurus papillomavirus 13JQ798171BPV13
Deltapapillomavirus 4Bos grunniens papillomavirus 1QH-1JX174437BgPV1
Deltapapillomavirus 4Bos taurus papillomavirus 14CGKnose1KP276343BPV14
Deltapapillomavirus 4Bos taurus papillomavirus 2M20219BPV2
Deltapapillomavirus 5Capreolus capreolus papillomavirus 1EF680235NC_011051Complete genomeCcaPV1
Deltapapillomavirus 5Rusa alfredi papillomavirus 1DE1641-14KT626573RalPV1
Deltapapillomavirus 6Camelus dromedarius papillomavirus 1HQ912790NC_015267Complete genomeCdPV1
Deltapapillomavirus 6Camelus dromedarius papillomavirus 2HQ912791CdPCV2
Deltapapillomavirus 7Giraffa camelopardalis papillomavirus 1GC2011KX954132NC_039036Complete genomeGcPV1

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.