Subfamily: Betairidovirinae

Subfamily: Betairidovirinae

Distinguishing features

Virions within this subfamily are larger than vertebrate iridoviruses, contain generally larger genomes that lack the extensive cytosine methylation seen among vertebrate iridoviruses, display lower G+C content, and infect mainly invertebrate hosts. Furthermore, virions within this subfamily often display fiber-like extensions extending from the capsid. Although they infect a wide range of agricultural pests and medically important insects (e.g., mosquitoes), their study has, by and large, been neglected and important information regarding host range, number of viral species, and replication strategy is incomplete (Williams and Ward 2010, Williams et al., 2016).

Genus demarcation criteria

Historically members of the two genera were distinguished by virion size and the iridescent color of infected insects and purified virus stocks. Given increasing numbers of fully sequenced viral genomes within this subfamily, membership within, and composition of, the two genera will likely require revision as phylogenetic analysis (Figure 6.Iridoviridae) suggests alternative interpretations.

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