Genus: Macavirus

Genus: Macavirus

Distinguishing features

The predicted amino acid sequences of members form a distinct lineage within the subfamily (Figure 1.Gammaherpesvirinae).


See discussion under family description.

Genome organization and replication

See discussion under family and subfamily description.


Members have artiodactyls (even-toed ungulates) as hosts. Several members are responsible for inducing an often fatal, generalised lymphoproliferative disease, known as malignant catarrhal fever (MacLachlan et al., 2016, Russell et al., 2009).

Species demarcation criteria

See discussion under family description.

Member species

Exemplar isolate of the species
SpeciesVirus nameIsolateAccession numberRefSeq numberAvailable sequenceVirus Abbrev.
Alcelaphine gammaherpesvirus 1alcelaphine gammaherpesvirus 1; wildebeest-associated malignant catarrhal fever virusC500AF005370NC_002531Complete coding genomeAlGHV1; MCFV
Alcelaphine gammaherpesvirus 2alcelaphine gammaherpesvirus 2; hartebeest-associated malignant catarrhal fever virustopi-AlHV-2KF274499NC_024382Complete genomeAlGHV2
Bovine gammaherpesvirus 6bovine gammaherpesvirus 6; bovine lymphotropic herpesvirusPennsylvania 47KJ705001NC_024303Complete genomeBoGHV6; BLV
Caprine gammaherpesvirus 2caprine gammaherpesvirus 2; caprine herpesvirus 2AF283477NC_043059Partial genomeCpGHV2; CpHV2
Hippotragine gammaherpesvirus 1hippotragine gammaherpesvirus 1; roan antelope herpesvirusDQ083950NC_043060Partial genomeHiGHV1
Ovine gammaherpesvirus 2ovine gammaherpesvirus 2; sheep-associated malignant catarrhal fever virusBJ1035AY839756NC_007646Complete genomeOvGHV2
Suid gammaherpesvirus 3suid gammaherpesvirus 3; porcine lymphotropic herpesvirus 156AF478169NC_038264Partial genomeSuGHV3; PLVH1
Suid gammaherpesvirus 4suid gammaherpesvirus 4; porcine lymphotropic herpesvirus 2568AY170317NC_038265Partial genomeSuGHV4; PLHV2
Suid gammaherpesvirus 5suid gammaherpesvirus 5; porcine lymphotropic herpesvirus 3489AY170316Partial genomeSuGHV5; PLHV3

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.