Genus: Proboscivirus

Genus: Proboscivirus

Distinguishing features

The predicted amino acid sequences of members form a distinct lineage within the subfamily (Figure 1.Betaherpesvirinae). This lineage appears to have been the earliest to branch within the subfamily.


See discussion under family description.

Genome organization and replication

See discussion under family and subfamily description.


Members have elephants as hosts. Infection is associated with cases of highly lethal acute haemorrhagic disease, which is largely confined to Asian elephant calves and is predominantly associated with elephantid endotheliotropic herpesvirus 1 (in the species Elephantid betaherpesvirus 1 (Long et al., 2016)).

Species demarcation criteria

See discussion under family description.

Member species

Exemplar isolate of the species
SpeciesVirus nameIsolateAccession numberRefSeq numberAvailable sequenceVirus Abbrev.
Elephantid betaherpesvirus 1elephantid betaherpesvirus 1; elephantid endotheliotropic herpesvirus 1RamanKC462165NC_020474Complete genomeElBHV1; EEHV1
Elephantid betaherpesvirus 4elephantid betaherpesvirus 4; elephantid endotheliotropic herpesvirus 4NAP69KT832477NC_028379Complete genomeElBHV4; EEHV4
Elephantid betaherpesvirus 5elephantid betaherpesvirus 5; elephantid endotheliotropic herpesvirus 5VijayKF921519NC_024696Complete genomeElBHV5; EEHV5

Virus names, the choice of exemplar isolates, and virus abbreviations, are not official ICTV designations.