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The Corticoviridae is a family of icosahedral internal membrane-containing viruses with double-stranded circular DNA genomes of ~10 000 bases in length. Only one virus species, Pseudoalteromonas virus PM2, has been recognized. Bacteriophage PM2 infects Gram-negative bacteria. Currently, PM2 does not share any significant sequence similarity to any other virus. PM2 was isolated from seawater in 1968 and was already reported in the 1st Report of ICTV. PM2 is the first bacteriophage in which the presence of lipids in the virion was demonstrated. Since only one genus Corticovirus is recognized, the family description corresponds to the genus description.
PM2 is a virulent virus infecting Gram-negative Pseudoalteromonas species (Espejo & Canelo, 1968; Kivelä et al., 1999). The characteristic feature of the corticovirus is the highly supercoiled circular double-stranded DNA genome. The virions are composed of an icosahedral protein capsid and an internal protein-rich membrane enclosing the genome (Abrescia et al., 2008). PM2 does not share significant sequence similarity to any other virus.
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